Could people’s eyes and ears help fix the damage Alzheimer’s disease does to the brain? Just by looking at flashing light and listening to flickering sound? A new study led by a prominent M.I.T. neuroscientist offers tantalizing promise. It found that when mice engineered to exhibit Alzheimer’s-like qualities were exposed to strobe lights and clicking […]
Scientists found that when mice engineered to exhibit Alzheimer’s-like qualities were exposed to flickering lights and 40Hz sounds for one hour a day, their brain functions improved and toxic levels of Alzheimer’s-related proteins diminished. In addition, the 40Hz sound appeared to improve cognitive and memory skills. Light and sound delivered at a certain frequency —40 […]
A brain training computer game developed by British neuroscientists has been shown to improve the memory of patients in the very earliest stages of dementia and could help such patients avert some symptoms of cognitive decline. Read the full article
Changes in gamma oscillations (20–50 Hz) have been observed in several neurological disorders. However, the relationship between gamma oscillations and cellular pathologies is unclear. Here we show reduced, behaviourally driven gamma oscillations before the onset of plaque formation or cognitive decline in a mouse model of Alzheimer’s disease. Optogenetically driving fast-spiking parvalbumin-positive (FS-PV)-interneurons at gamma (40 Hz), […]
When brain cells fire rhythmically and in sync, they produce waves, which are categorized by their firing frequencies. Delta waves (1.5 Hz to 4 Hz), for example, are produced during deep sleep, theta waves (4 Hz to 12 Hz) occur during running and deep meditation, and gamma waves (25 Hz to 100 Hz) are associated […]
Experimental drugs from some of the world’s top pharmaceutical companies have so far failed to halt the march of Alzheimer’s disease, a neurodegenerative disorder that gradually robs people of their memory and cognition. Now scientists are trying an audacious approach that doesn’t involve medicines of any kind: They’re using LED beams to disrupt gamma waves […]
A flashing light therapy might help ward off Alzheimer’s, say US scientists after promising trials in mice. The Massachusetts team found shining a strobe light into rodents’ eyes encouraged protective cells to gobble up the harmful proteins that accumulate in the brain in this type of dementia. The perfect rate of flashes was 40 per […]
Background Cognitive impairments, particularly memory problems, are a defining feature of the early stages of Alzheimer’s disease (AD) and vascular dementia. Cognitive training and cognitive rehabilitation are specific interventional approaches designed to address difficulties with memory and other aspects of cognitive functioning. The present review is an update of previous versions of this review. Objectives […]
The present paper presents data from ten patients suffering from mild to moderate Alzheimer’s disease (AD), all of whom were trained to use an interactive computer-based program. Using photographs of the patient and his or her personal surroundings, an everyday task of relevance to the patient was simulated on a PC-touch screen, which the patient […]
Results Significant time-by-pattern-by-group interactions were found for cognitive performance in terms of the number of errors made and trials needed on the Cambridge Neuropsychological Test Automated Battery Paired Associates Learning task (P=.044; P=.027). Significant time-by-group interactions were also found for the Cambridge Neuropsychological Test Automated Battery Paired Associates Learning first trial memory score (P=.002), Mini-Mental […]
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