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Brain Training with 40Hz Gamma Light and Sound

New research suggests that light and sound delivered at a certain frequency —40 flashes or clicks per second — appear to restart the natural 40Hz gamma rhythm of the brain and improve the brain functions. You can see the results from the first human study published in PLOS ONE.

Separately, research has also shown that cognitive exercises could have a major effect on improving memory. The synergistic combination of 40Hz gamma light, sound and brain training games has the potential to improve the brain’s function better than either of these approaches  alone.

How It Works

AlzLife delivers a combination of 40Hz light, 40Hz sound, and cognitive exercises in a single, easy-to-use, convenient package.

Brain Games

  • Your favorite brain games: Sudoku, Tic-Tac-Toe, Clocks, Memory Games
  • Designed specifically for older people with minimal computer skills
  • Cognitive games for every level, from very easy to difficult
  • 40Hz gamma light available around a game screen or in full-screen
  • 40Hz sound

Life Coach

  • Guided meditations to help you relax
  • Powerful exercises to help you stay in shape
  • Soothing bedtime stories to help you fall into a deep and natural sleep
  • Daily Planner with a personalized checklist
  • Conversation starters to provide ideas for lively conversations

40Hz Gamma Light & Sound

  • 40Hz Gamma Light & Sound is available while playing cognitive games
  • Pure 40Hz Gamma Light is available in full-screen and off-line
  • Position the iPad nearby and experience Pure 40Hz Gamma Light while occupied with any activity
  • Large, curated library of educational videos available with 40Hz Gamma Light around a video frame

The Neurological Mechanism

Light and sound delivered at a certain frequency —40 flashes or clicks per second — appear to restart the natural 40Hz gamma rhythm of the brain. This gamma rhythm is essential for local neuronal communication and is associated with concentration and cognitive activity. Neurons in the cortex usually work in groups and are a bit analogous to a musical orchestra. When music instruments synchronize we hear a pleasant melody, but when they desynchronize we hear a cacophony of sounds a little like the tuning up of an orchestra. Similarly, when there is no normal brain rhythm, neurons fire out of sync and cannot generate coherent group decisions.

AlzLife is based on US Patent Pending: 62/606,112 and 62/606,476

This app has not been approved by FDA for cure, mitigation, treatment, or prevention of disease. It is intended for maintaining and encouraging a healthy lifestyle.

How To Use Your AlzLife App

We recommend using your AlzLife app for one hour a day. If the 40Hz gamma frequency flicker is too bothersome, start using the app with the 40Hz light settings set to a minimum. Most people will get used to the flicker over several sessions. If you stop noticing the flicker, you may want to increase the intensity within the app’s Setting.

The game portion of the app was specifically designed for memory and cognitive improvement. Start with games you are familiar with, then continue with as many games as possible. We recommend starting at an easy level and slowly increasing the game difficulty to a level that is challenging but not uncomfortable.

 

Some people who are susceptible to seizures may react negatively to gamma light.  If you have had seizures in the past, we suggest that you avoid using this application before consulting your primary doctor.

What devices can I use AlzLife on?

The 40Hz light function of AlzLife requires the refresh rate of your device’s screen to be greater than 80 Hz. As of August 2024, the list of devices with the required refresh rate includes:

Apple devices: 

Android devices (Settings > Battery > Power Saving > Disable Power Savings, to allow greater screen refresh rate necessary for 40 Hz light)

  • Google Pixel 4 and later
  • Samsung Galaxy S20, A54, Galaxy Note 20 and later
  • Asus ROG Phone 2 and later
  • OnePlus 7T, 7T Pro, OnePlus 7 Pro and later
  • Realme X2 Pro, Poco X2, X50, 6 Pro, 6 and later
  • Nubia Red Magic 3S and later
  • Xiaomi Mi 10, 10 Pro 5G and later
  • Razer Phone 2 and later
  • Sharp Aquos Zero2, Aquos R1 and later
  • Blackview BV8100, Shark8 and later
  • Motorola Moto G and later
  • NUU A25 and later
  • REDMAGIC 9 Pro and later
  • Honor Magic 3 Pro and later
  • Huawei Mate 50 Pro, P50 Pro, Pura 70 Pro and later
  • Sony Xperia
  • Xiaomi 10 and later

Android Tablets

  • Huawei’s MatePad Pro 12.2, 13.2 (2024) and later
  • Honor MagicPad 2 and later
  • NEC Lavie Tab T14 and later
  • Samsung Galaxy Tab S9 and later

What games can I play in AlzLife?

AlzLife includes Your favorite cognitive games:

  • Chess (AI chess from easy to challenging)
  • Sudoku (from easy 4×4 to challenging 9×9)
  • Tic-Tac-Toe (from easy to challenging)
  • Clock Game (from easy to challenging)
  • Cognitive blocks (from easy to challenging)
  • Memory Games
  • Driving Reaction
  • Solitaire
  • Jewel Crush
  • Word Search
  • Checkers
  • Backgammon
  • Wordoku
  • A library of 10,000+ free books
  • + many other brain games

Science

The proof is in the data

New study finds synergy between 40Hz stimulation and cognitive activities

New study finds synergy between 40Hz stimulation and cognitive activities. Inclusion of a cognitive task during the 40Hz stimulation not only has a positive effect on the strength and extent of the gamma entrainment, but also promotes the propagation of gamma entrainment to additional neural areas including deep ones such as hippocampus which were not recruited when no cognitive task was required from the participants. The latter is of particular importance given that the hippocampal complex is considered to be one of the primary targets for Alzheimer’s disease therapies.

Results from the first human study of the effect of 40Hz light/sound stimulation have been published

Results from the first human study of the effect of 40Hz light/sound stimulation have been published. After 3 months of daily stimulation, the group receiving 40Hz stimulation showed (1) lesser ventricular dilation and hippocampal atrophy, (2) increased functional connectivity, (3) better performance on a memory test, and (4) improved sleep and measures of daily activity.

TED talk by Professor Li-Huei Tsai: Could we treat Alzheimer’s with light and sound?

Dr. Li-Huei Tsai details a promising new approach to artificially stimulate gamma brain waves using light and sound therapy, to increase connectivity and synchrony and delay the onset of this deadly disease.

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